HMB is clinically studied to support lean muscle during periods of reduced intake
HMB's role in preserving lean mass and strength during weight loss is supported across clinical reviews, including a 2025 narrative review on supplementation during reduced-calorie/GLP-1 weight loss (Dietary supplement considerations…, ScienceDirect, 2025) and HMB muscle-wasting RCTs (e.g., Nutrients, 2022)